The Greenville County Health Department phone number is (864) 372-3270. The clinic is at 352 Halton Road, Greenville, SC 29607, and it is open weekdays from 8:30 a.m. to 5 p.m. To book a clinical appointment, you can also call the statewide South Carolina Department of Public Health appointment line at (855) 472-3432 or use the Web Chat on the DPH website.1South Carolina Department of Public Health. Public Health Clinics
Why the Old DHEC Number May Not Reach You
On July 1, 2024, the South Carolina Department of Health and Environmental Control was abolished and split in two. Clinical services moved to the new South Carolina Department of Public Health (DPH). Septic permits, well water, and other environmental programs moved to the Department of Environmental Services (DES). Retail food safety moved to the SC Department of Agriculture.2South Carolina Department of Public Health. Historical: S.C. Board of Health and Environmental Control
The old general DHEC line (864-282-4100) may no longer land you where you expect. Each new agency runs its own phone lines, so matching your issue to the right agency before you dial saves a transfer.
Clinical Appointments at the Halton Road Clinic
The main clinic number, (864) 372-3270, reaches the Greenville County office of DPH. For scheduling, the statewide appointment line at (855) 472-3432 also covers the Greenville clinic and nearby satellite offices.1South Carolina Department of Public Health. Public Health Clinics
Services offered through the clinic include:
- Childhood and adult immunizations
- Family planning
- STD, HIV, and Hepatitis C testing and treatment
- Tuberculosis treatment
- PrEP and STI PEP (doxyPEP)
- Opioid overdose kits with naloxone
- WIC services
Not every service runs at every location, so call ahead to confirm before you drive out.
WIC Phone Numbers
Greenville County has WIC offices in several locations. The Greenville Center for Pediatric Medicine WIC office has a direct line at (864) 522-5220. The WIC fax for the Greenville County office is (864) 282-3823. Additional WIC offices operate in Greer, Simpsonville, and Slater, and all of them schedule through the same statewide line at (855) 472-3432.1South Carolina Department of Public Health. Public Health Clinics
WIC serves pregnant women, new mothers, infants, and children up to age five, with food benefits, nutrition counseling, and referrals. For a first appointment or an eligibility question, the statewide number is usually the fastest route.
Birth and Death Certificates
The Vital Records Division works out of the same 352 Halton Road address.3Greenville County. Birth Certificates A $12 nonrefundable search fee covers the first certified copy if the record is found. Each additional copy of the same record ordered at the same time is $3. The $12 fee is not refunded even if no record is located.4South Carolina Department of Public Health. Fees – Vital Records (Birth, Death, etc)
If you need a certificate for something specific, like a passport application, tell staff when you call so they can confirm the document meets the requirements.5South Carolina Department of Public Health. Birth Certificates
Septic Permits, Well Water, and Food Inspections
Don’t call the health department for these. Septic tank permits, well water testing, and related environmental inspections are now handled by the SC Department of Environmental Services. The Greenville-Spartanburg DES regional office covers Cherokee, Greenville, Pickens, Spartanburg, and Union counties.6South Carolina Department of Environmental Services. Locations
The DES Greenville number is (864) 372-3273, at 660 Mauldin Road, Suite 100, Greenville, SC 29607. Contractors applying for septic permits and homeowners with well water concerns should call that line directly.7Greenville County. Septic Tank Application Notice Restaurant inspections and food service permits go through the SC Department of Agriculture, not DES or the health department.
All the Numbers in One Place
- Greenville County Health Department (DPH clinic): (864) 372-3270
- Statewide DPH appointment line: (855) 472-3432
- WIC direct line (Pediatric Medicine office): (864) 522-5220
- WIC fax (Greenville County): (864) 282-3823
- Environmental Services (DES Greenville): (864) 372-3273
- SC DPH state office (Columbia): (803) 898-3300
The clinic and the DES office sit at different addresses: 352 Halton Road for health services, 660 Mauldin Road, Suite 100 for environmental matters. Both are in Greenville, but confirm which agency handles your issue before an in-person visit.1South Carolina Department of Public Health. Public Health Clinics6South Carolina Department of Environmental Services. Locations If you have a hearing impairment, dial 711 for South Carolina’s relay service to reach any of the numbers above.